Read stories of how our people apply heart and science to solve complex challenges, deliver breakthroughs in the face of the toughest obstacles, and make the world a healthier place for patients everywhere.

Chris, Lauryn,
Carson Rose,
& AJ Tubesing

Chris, Lauryn, Carson Rose, & AJ Tubesing

Made
For

Hope And Family

  • API
  • Biologics
  • Early & Late Phase Development
  • Clinical Trial Solutions
  • Logistics Services
  • Commercial Manufacturing

HOW A FAMILY’S PERSEVERANCE HELPED THEM REACH A SEEMINGLY UNATTAINABLE GOAL.

As members of the United States Air Force, Lauryn and Chris were as healthy and fit as a young couple could be. But in the world of genetics, all it takes is a couple of proteins lining up in the wrong way, and things can change in a hurry. They found that out when two of their three children tested positive for Cystic Fibrosis (CF). Lauryn and Chris were both carriers of mutations that, when combined, caused the disease. So an active life was replaced with one of endless treatments, trips to the doctor and fear of catching even the slightest cold. Plus the knowledge that life expectancy for patients with CF was typically about 31. Something no parent wants to hear. They learned of a “wonder drug” helping CF patients – one that actually treated the underlying causes of the disease, not just the symptoms. Best of all, it was manufactured in their backyard in Reading, Ohio. After about 6 months of taking the medicine, their doctor said something they hadn’t heard before: “Your daughter looks healthy.” And best of all, life expectancy for patients who respond to this therapy is now into the 60s and beyond. So these two veterans can now look forward to all the dreams that parents have for their kids, including a long life and children of their own some day.

Nicole and Gavin Pierson

Nicole and Gaving Pierson

Made
For

男人色a V 日本色v A 网Compassion & Courage

  • API
  • Biologics
  • Early & Late Phase Development
  • Clinical Trial Solutions
  • Logistics Services
  • Commercial Manufacturing

HOW ONE INCREDIBLY BRAVE KID INSPIRED A ONE OF A KIND CLINICAL TRIAL.
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男人色a V 日本色v A 网Gavin had late stage brain cancer and not a lot of time. Chemotherapy and surgeries were not working, and Nicole was desperate to find a way to save her son. She knew of a drug in clinical trial that was showing promising results in adults, so she contacted the manufacturer and made her case for Gavin. The manufacturer agreed to let Gavin take the drug, but as a child he couldn’t participate in the existing trial. They needed to create a special trial so he could participate. Fisher Clinical Services, by Thermo Fisher Scientific, and the drug company worked together to create a special clinical trial, just for him. For the next two and half years, Thermo Fisher delivered Gavin’s individual dose on time, every time. The result was astounding. Not only did the tumor stop growing, it actually shrunk. And Gavin? He’s able to be a kid again, attending school, playing with friends and taking karate class. He’s now a brown belt in karate, going for black.

Hui Wang, Ph.D.
Operations Support Engineer,
Pharma Services,

男人色a V 日本色v A 网Brisbane, Australia

Hui Wang

Delivered
With

Agility & Fluency

  • API
  • Biologics
  • Early & Late Phase Development
  • Clinical Trial Solutions
  • Logistics Services
  • Commercial Manufacturing

HOW SPEAKING A THIRD LANGUAGE HELPED WIN THE RACE TO MARKET.
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男人色a V 日本色v A 网Several Chinese pharmaceutical companies were competing to be first to market. And second place didn’t matter. Hui Wang, from Thermo Fisher’s Brisbane, Australia site, had a client trying to become the first Chinese pharmaceutical company to bring a cancer drug to the U.S. market. The complication? They’re a Chinese company who has never done business in the west. Clearly translators would have to keep things moving. But speaking both Mandarin and English wasn’t enough. With speed at a premium and a tech transfer document needed asap, Hui also needed to be fluent in the language of science. With her extensive scientific and manufacturing background, she worked with client teams, translating technical information in real time. So the process never slowed down. In fact, instead of taking the typical two months, the initial tech transfer document was ready in two weeks. Allowing her client to win that race.

Marcus Roberts
Senior Manager, Quality,
Pharma Services,

男人色a V 日本色v A 网Memphis, TN

Marcus Roberts

Delivered
With

男人色a V 日本色v A 网Initiative & Insight

  • API
  • Biologics
  • Early & Late Phase Development
  • Clinical Trial Solutions
  • Logistics Services
  • Commercial Manufacturing

HOW ONE SPLIT-SECOND DECISION MADE A DIFFERENCE FOR THOUSANDS OF PATIENTS.
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In the world of drug manufacturing not all life-saving decisions happen in the lab. Sometimes it’s a lot closer to delivery that key moments require fast thinking. Such as one Saturday morning in Memphis, TN, when Marcus noticed the freezer temperatures were out of range. With over 2,000 cold chain shipments leaving his facility per day, he couldn’t afford to lose a week’s supply due to warm temperatures. As the repair crew worked on the issue, Marcus knew it wasn’t an easy fix and he needed a backup. So he had to make a call, on a weekend, without time to consult the chain of command. Soon, Marcus had a few freezer trailers on site, and an emergency work crew helping to load ice into them, so they could keep the week’s supply safe. And on Sunday, when he got the notification that the main freezer was having issues again, he knew he had made the right call. Today, the freezer is fully operational, and such issues are rare. However, we now keep extra freezer trailers on site permanently as a back-up, just in case.

Yoonhee Ko
Senior Business
Development Manager,
Pharma Services,

South Korea

Yoonhee Ko

Solved
With

男人色a V 日本色v A 网Power & Process

  • API
  • Biologics
  • Early & Late Phase Development
  • Clinical Trial Solutions
  • Logistics Services
  • Commercial Manufacturing

HOW COMING TOGETHER AS ONE LOCAL TEAM DELIVERED AN INTERNATIONAL SOLUTION.

A Korean client was wary of working with a global manufacturing and outsourcing partner because of perceived complications. Different departments, divisions and regions would surely create multiple teams, workflows and contracts to sort through. They believed it would be better to handle as many of the steps themselves as they possibly could. But Yoonhee knew the power of collaboration across Thermo Fisher’s Patheon and Fisher Clinical Services businesses would ensure success. While tirelessly working to ensure a seamless experience for her client, Yoonhee brought together multiple project managers into one team. From there, they coordinated the end-to-end process, from IP manufacturing through supply chain. The client saved months in the process. And now, Thermo Fisher offers one integrated program team under one umbrella CDA and MSA to save clients time and energy right from the start.

Francis Vazquez
General Manager,
Pharma Services,

男人色a V 日本色v A 网Manati, PR

Hui Wang

Made
With

男人色a V 日本色v A 网Character & Commitment

  • API
  • Biologics
  • Early & Late Phase Development
  • Clinical Trial Solutions
  • Logistics Services
  • Commercial Manufacturing

HOW HUNDREDS OF PEOPLE CAME TOGETHER TO PULL OFF THE IMPOSSIBLE.

When Hurricane Maria hit the island of Puerto Rico as a Category 4 storm, it decimated everything. The entire island was knocked off the grid. No power. No fuel. No water. No food. No communications. Roads were blocked and people everywhere struggled in an environment of complete turmoil. As the General Manager of Thermo Fisher’s drug manufacturing site in Manati, Puerto Rico, Francis had a seemingly insurmountable challenge ahead of him. But with his calm demeanor, he took it one step at a time. First priority, find his people. Make sure they and their families are safe. Next, get to the site, begin the process of bringing it back. Then, establish communications by setting up a network of information distribution until cell service could return (weeks later). Give the growing list of employees managing to show up for work, despite all that was going on in their lives, more and more jobs to get the facility operational again. Keep clients informed of daily developments and goals. And most important, get the equipment up and running so that patients around the world didn’t go without their life-saving medications. Francis even opened the facility to locally-based clients on the island who needed a place to work. And finally, with the full efforts of his whole team, the facility was back online two months after the storm. It just goes to show how far you can go with commitment, teamwork and a ton of heart.

Adamou Seydou
Gelatin Associate,
Pharma Services,

男人色a V 日本色v A 网High Point, NC

Adamou Seydou

Delivered
With

Ingenuity & Insight

  • API
  • Biologics
  • Early & Late Phase Development
  • Clinical Trial Solutions
  • Logistics Services
  • Commercial Manufacturing

HOW WASTED MATERIAL INSPIRED SAVING TIME AND MONEY.
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男人色a V 日本色v A 网When it comes to manufacturing softgel dosage forms, nobody knows more about operating the equipment that makes them than Adamou. He’s relentless about finding new ways to make the manufacturing process more efficient. So, when he saw the amount of scrap material being produced during a specific manufacturing process, he was determined to find a way to decrease it. He enlisted the help of a team of experts who supported his cause and they worked after hours and weekends until they found a solution. The result is a new process that greatly reduces scrap, delivers savings to customers, and most importantly, helps to lower the cost of medicines for the patients who need them.

Tony Pidgeon
Director, Business Management
Pharma Services,

Swindon, UK

Tony Pidgeon

Solved
With

Protocols & Passion

  • API
  • Biologics
  • Early & Late Phase Development
  • Clinical Trial Solutions
  • Logistics Services
  • Commercial Manufacturing

HOW HALF THE BATCHES ACHIEVED TWICE THE RESULTS.
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Sometimes, the future of a client’s entire company is riding on the success of one trial. That was the case when a small client came to Tony looking for a formulation solution for a revolutionary treatment. The problem was, their clinical trial protocol, as originally written, required six blinded doses. But the client could only afford to produce three batches, not six. If they couldn’t complete this trial milestone, the company was at risk of going out of business. When the client presented Tony with the issue, he recommended an adjustment to the trial protocol that would ensure they could gather the clinical data they needed with just three batches. By changing the clinical protocol, the trial the client thought was beyond their reach, suddenly became possible. And now this small company could move forward to make a big impact.

Whitney Sandberg
Sr. Director, Quality,
Pharma Services,

St. Louis, MO

Whitney Sandberg

Made
With

男人色a V 日本色v A 网Flexibility & Focus

  • API
  • Biologics
  • Early & Late Phase Development
  • Clinical Trial Solutions
  • Logistics Services
  • Commercial Manufacturing

HOW SHORT-TERM FLEXIBILITY ENABLES LONG-TERM SUCCESS.
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When a client tells us that our internal processes are getting in the way of meeting their needs, we take it to heart. That’s the position Whitney faced when her client felt that her facility, originally designed for GMP biologic drug substance commercial manufacturing, was too rigid for the fast-paced, rapidly-changing world of clinical manufacturing. So, she pulled together a cross-functional team that included Quality, Tech Transfer, and Biological Sciences, to take a new look at their commercial quality processes to determine how they could appropriately adapt them to meet the unique needs of their clients in development phases. And the change worked. Now her facility can deliver the robust and reliable commercial process it has always been known for, as well as the more flexible, faster-turn execution needed for clinical. Best of all, her clients can get to clinical trial faster and expedite delivering medicines to the patients who need them most.

Sanjay Konagurthu, Ph.D.
Sr. Director, PDS Global
Science & Technologies
Pharma Services,

男人色a V 日本色v A 网 Bend, OR

Sanjay Konagurthu

Solved
With

Chemistry & Conviction

  • API
  • Biologics
  • Early & Late Phase Development
  • Clinical Trial Solutions
  • Logistics Services
  • Commercial Manufacturing

HOW TAKING THE EDGE OFF A CRYSTAL GAINED AN ADVANTAGE.
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Sometimes, even if your job focuses on data, you have to look beyond it. That’s why Sanjay and his team at Thermo Fisher Scientific don’t just apply data to solve formulation challenges. They look beyond the data for other potential roadblocks. In the early phase trials of a complex API molecule, his team recognized that dagger shaped crystals were inhibiting flow during production. While short-term workarounds for trials were at hand, they knew that in future scale ups, this would become a significant problem. So they collaborated with teams who modified the API process in advance. Smoothed the crystal. And solved the problem before it became one.

Angie West
Global Relationship Director,
Pharma Services,

Allentown, PA

Angie West

Delivered
With

Capacity & Compassion

  • API
  • Biologics
  • Early & Late Phase Development
  • Clinical Trial Solutions
  • Logistics Services
  • Commercial Manufacturing

HOW A COMBINATION OF TEAMWORK, HEART, AND SCIENCE ENSURED THOUSANDS OF PATIENTS AROUND THE GLOBE DIDN’T GO WITHOUT MEDICINE.
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Angie will never forget the day she got a call from a client with a packaging and logistics challenge of global proportions. They needed her help figuring out how to get an oncology drug labeled for 60,000 patients in 35 countries every month. And they needed that solution to fit in a four week cycle – half the time typically required to turn around a trial of that scale. So, Angie pulled together a team of experts across 10 departments to break down every step of the process. They worked long hours and explored every possible opportunity to increase efficiencies and take time out of the process. Then they set up an operator training lab to ensure everyone on the team could deliver the new solution as planned. The result was a 55% reduction in cycle times and thousands of patients around the world received the life-saving medication they needed.

Mike Cruskie
VP & GM API Operations
North America,
Pharma Services,

Florence, SC

Mike Cruskie

Solved
With

男人色a V 日本色v A 网Science & Service

  • API
  • Biologics
  • Early & Late Phase Development
  • Clinical Trial Solutions
  • Logistics Services
  • Commercial Manufacturing

HOW ON ANY GIVEN DAY, A SUIT JACKET CAN BECOME A LAB COAT.

When a client’s molecule experienced a problem during scale up at Mike’s API facility, he did exactly what any Thermo Fisher Scientific general manager would do: he put on his lab coat and got to work. As a process chemist who spent many years in the lab himself, Mike is uniquely qualified to lead a team of API chemists, analysts, and operators. And when the situation requires it, he’s ready and able to jump in to solve complex problems like this one. And that’s exactly what they did. The cross-functional team uncovered the issue, minimized the batch waste, and gave a small company a shot at making it big.

Mandy Bosse
VP & GM Cincinnati
Regional Operations
Pharma Services,

Cincinnati, OH

Mandy Bosse

Delivered
With

男人色a V 日本色v A 网Capacity & Compassion

  • API
  • Biologics
  • Early & Late Phase Development
  • Clinical Trial Solutions
  • Logistics Services
  • Commercial Manufacturing

HOW 800 EMPLOYEES WORKING 3 SHIFTS FOR 365 STRAIGHT DAYS KEEP A SINGULAR FOCUS.
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男人色a V 日本色v A 网Managing a 24/7 facility that simultaneously handles more than 90 molecules requires a leader who understands development, manufacturing technology, operations, logistics and customer needs. But, if you ask Thermo Fisher Scientific site GM Mandy Bosse, she’ll tell you that the most important aspect of her job is to inspire. Which is why she regularly invites patients to her facility to speak to her team about the drugs they make every day. One such patient is Tyler, who suffers from nephropathic cystinosis, and takes a drug made at the facility to treat his disease. Tyler, who is surpassing patient life expectancy norms, didn’t come alone. He brought his wife who is expecting their first child. That’s a healthy dose of inspiration for a team whose work may be predicated on precision, but is fueled by compassion.

Jeff Hou, Ph.D.
Manager, Cell Culture
Development, Pharma Services,

男人色a V 日本色v A 网Princeton, NJ

Jeff Hou

Made
With

男人色a V 日本色v A 网Process & Purpose

  • API
  • Biologics
  • Early & Late Phase Development
  • Clinical Trial Solutions
  • Logistics Services
  • Commercial Manufacturing

HOW A SMALL STARTUP WAS ABLE TO SCALE UP, WITHOUT LOSING THEIR PRECIOUS MATERIAL.

Jeff faced a dilemma: how to complete a large biomanufacturing scale up with the very small amount of material his client gave him. And the stakes were high. His client had spent a lot of time and money developing this potentially revolutionary Alzheimer’s treatment. Any wasted material would put the execution of the clinical trial at risk, and possibly risk the future of the entire program. Jeff knew the process needed to be perfect. So, his team worked tirelessly to find ways to improve the cell culture performance. They examined key process parameters and even completed additional work in the process development laboratory to ensure success. The result was a flawless scale up and, most importantly, a potentially breakthrough drug was able to get into the clinic.

Michael Stanek, Ph.D.
VP Business Management,
API Pharma Services,

Linz, Austria

Michael Stanek

Solved
With

男人色a V 日本色v A 网Optimization & Optimism

  • API
  • Biologics
  • Early & Late Phase Development
  • Clinical Trial Solutions
  • Logistics Services
  • Commercial Manufacturing

HOW MONITORING THE BOTTOM LINE INSPIRED A LEADING-EDGE SOLUTION.
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男人色a V 日本色v A 网While observing the API manufacturing process for a client, Michael wasn’t happy with what he saw. The purification process was inefficient, unnecessarily driving up costs. So, he got to work analyzing the entire process and his ideas were tested in the lab. The improvements discovered were so impressive that the client agreed to test the process at a larger scale. After another successful outcome, they decided to implement the refinements across the entire manufacturing process. The result not only reduced impurities and cut costs, it enabled capacity improvements which allowed greater control to manage larger volumes.

Shawn Regits
Manager, Process Engineering,
Pharma Services,

男人色a V 日本色v A 网Allentown, PA

Shawn Regits

Made
With

Accuracy and Action

  • API
  • Biologics
  • Early & Late Phase Development
  • Clinical Trial Solutions
  • Logistics Services
  • Commercial Manufacturing

HOW A SIMPLE PROCESS BUILT PERFECT PERFORMANCE.
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When a client required the 100% error-free assembly of syringes that included a backstop, Shawn knew his operations team would require a new process. The current process required multiple steps, each with the potential to risk deviation. A deviation could quarantine the job and risk medicine not being delivered on time. The solution was a smart and simple error-proofing tool Shawn designed and built, which replaced several steps in the process. The tool allowed only syringes with a backstop to continue through the line. Several months after implementation, there are zero deviations and shipments are out the door faster than anticipated.

Eric Jayjock, Ph.D.
Director of Continuous Manufacturing
Pharma Services,

男人色a V 日本色v A 网Greenville, NC

Eric Jayjock

Solved
With

Vision & Precision

  • API
  • Biologics
  • Early & Late Phase Development
  • Clinical Trial Solutions
  • Logistics Services
  • Commercial Manufacturing

HOW CONTINUOUS EFFORT BROUGHT CONTINUOUS MANUFACTURING TO THE NEXT LEVEL.
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Eric had a vision that could change the face of drug manufacturing – if he could make it a reality. As a post doctorate, he had already perfected the process of continuous manufacturing for one drug. When he joined Thermo Fisher Scientific, he took on a much bigger challenge: creating a continuous manufacturing platform that could operate using interchangeable components, creating a solution that delivered the efficiency of a continuous process, with the flexibility to adapt to multiple types of drugs for multiple clients. So, he and his team relentlessly designed, tested and built individual components of the interchangeable platform to bring to create a first-of-its-kind modular solution that worked flawlessly. Now any Thermo Fisher client can take advantage of this custom technology.

Isabelle Lafosse
Director, Global Technology Transfer
Pharma Services,

Cincinnati, OH

Isabelle Lafosse

Delivered
With

男人色a V 日本色v A 网Power & Partnership

  • API
  • Biologics
  • Early & Late Phase Development
  • Clinical Trial Solutions
  • Logistics Services
  • Commercial Manufacturing

HOW A GLOBAL NETWORK PROVIDES A GENUINE ADVANTAGE.
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男人色a V 日本色v A 网When a client gets an opportunity to expand rapidly, it takes a global partner to pull it off without a hitch. That’s what happened when Isabelle’s client received approval for a second indication for a drug that Thermo Fisher Scientific’s Patheon business was making. She knew manufacturing volume would go up. Fast. Her fear was that the two sites currently making the product couldn’t handle the increased volume. So, she tapped into the power of her global team, and in partnership with the client, conducted multiple trials simultaneously across Thermo Fisher’s global manufacturing network. As a result, they found a third site that met the client’s regulatory filling specifications, and most importantly, met the growing patient demand.

Emily Anderson
Ph.D., Analytical R&D,
Pharma Services,

Florence, SC

Jessica Floyd
QC Lab Supervisor
Pharma Services,

Florence, SC

Emily Anderson & Jessica Floyd

Solved
With

男人色a V 日本色v A 网Chemistry & Collaboration

  • API
  • Biologics
  • Early & Late Phase Development
  • Clinical Trial Solutions
  • Logistics Services
  • Commercial Manufacturing

HOW IN A CULTURE OF KNOWLEDGE SHARING, A MENTOR PAVED THE WAY TO SUCCESS FOR THEIR MENTEE.
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At Thermo Fisher Scientific, we believe that knowledge belongs to everyone. So, years ago, when Emily worked with her intern, Jessica, in the analytical department, she taught her all she could, as freely as possible. Today, Jessica leads her own team in quality control. Because of her past experience, she is uniquely qualified to identify issues that might have otherwise been missed and everyone benefits. This unique culture of knowledge sharing is a big part of how we get medicine into the hands of patients faster.